V.H.POTTY
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Hunger abatment amongst poor people, where ever they live, is a major pre-requisite if world peace is to be ensured. This realization is slowly dawning on many of the rich nations and substantial aid money is being promised to strengthen the food production systems in many impoverished countries in Africa and Asia. It is true that supplying food to the needy ones from the surplus available in some of the rich countries does help to bring solace to millions starved of foods qualitatively and quantitatively but this cannot be a long term solution. New seed technologies ans sustainable food production only can enable the poor countries to attain self-sufficiency to any meaningful extent. There is a devious attempt to hook aid receiving countries on to the GM crop technology which can never be a sustaining proposition. Recent announcement by the UK to fund research in biotechnology area for solving world's food problem with financial support by an American private foundation has roped in India also to lend some respectability to their project labeled as a "cooperative" endeavor. It is not clear as to the institutions involved as the promoters claim it as a capacity building exercise as if such capacities do not exist in India. As the emphasis is on biotechnlogy, it will not be wrong to assume that focus will be on GM technology and how far this will be acceptable to the consumers is another matter.
"The new initiative will place particular emphasis on improving the sustainable production of staple food crops across sub-Saharan Africa and South Asia. These include cassava, maize, rice, sorghum and wheat. By placing significant emphasis on these crops the initiative partners expect to be able to improve food security and quality of life for the largest possible number of people. The initiative also aims to maximise the impact of the research funded by supporting a more comprehensive approach to improving productivity and yield, for example by tackling crop resistance to drought or flood. By funding international researchers tackling problems across different countries and regions promising research from one country can easily be shared and tested more widely in different regions and conditions to provide the widest possible benefit. Professor Douglas Kell, BBSRC Chief Executive, said: "Global society faces huge challenges in the coming years and securing safe, affordable and nutritious food for everyone is one of the biggest. Scientists and organisations across the world have the capabilities and expertise to make a real difference in meeting the global food security challenge but no single organisation or country can do this on its own. By working together and by coordinating our activity we can maximise the impact of our investment and of international science. The joint programme that we are announcing today is a groundbreaking example of how we can do so." Each project funded under the initiative will include partners from the UK and a developing nation. This approach, used by BBSRC and DFID in previous programmes, aims to build scientific capacity in developing countries, with the aim of developing research teams and projects that tackle other local scientific challenges".
As far as India is concerned capability already exists in the country as proven by the Green Revolution achieved decades ago making the country self-sufficient and if the aim is to 'train' personnel from poorer countries in technologies that will increase the yield of staple crops, the project may be relevant. On th other hand if it is intended to help India achieve any break-through in grain production, sufficient expertise as well as funds are already available in India.
Food fortification is an issue assuming importance in modern days because the food processing industry invariably causes much depletion of nutrients during conversion of raw foods into ready to eat end products. It is well known that even the basic processing techniques like milling of food grains removes major part of the nutrient "treasure" that is naturally endowed. If most of the foods in the market to day are fortified or enriched, one must thank the food industry. But it is another matter that these externally added nutrients may not be as readily absorbed by the human body as that present in natural grains. A typical case is iron supplementation where no matter what form of iron compound one adds in the food during processing, the efficacy of absorption is very low. Biofortification therefore is considered more efficient since the nutrients are generated through biotechnical means with better chance of utilization by the body. However the mode of achieving this goal will decide whether the new products will be acceptable to the consumer or not.
So a decade ago scientists began experimenting with a different approach: What if they tinkered with crops so that they naturally contained iron, zinc or vitamin A? And that's where our hero, the sweet potato, comes in. Orange sweet potatoes on our Thanksgiving tables are full of beta carotene, which the body turns into vitamin A. But our sweet potatoes don't grow well in Africa. Africans eat an estimated seven million tons of sweet potatoes a year, but theirs are white ones that lack vitamin A. So scientists cross-bred sweet potatoes until they came up with vitamin A-rich orange varieties that grow well in Africa. Hard-bitten health specialists go weak-kneed over them. More than 170,000 Ugandan and Mozambiquan families are now growing these sweet potatoes. And the sweet potato is just the first of a number of crops that have been bred or engineered to address micronutrient deficiencies. This mix of agriculture and nutrition is called biofortification, and it's one of the hot words in the global poverty lexicon. Also in the works are rice and wheat packed with zinc, pearl millet and beans with iron, bright orange corn and golden cassava that give people vitamin A. These crops are all in various stages of testing by HarvestPlus, a nonprofit based in Washington. The alliance is financed by the Bill and Melinda Gates Foundation, the World Bank, aid agencies from Canada, Britain and the United States, and the aim is to produce cheap seeds in the public domain. "Biofortification is slow, but it has a huge impact in the end," said Howarth Bouis, director of HarvestPlus. One of the questions, though, is this: Will rural Africans want to eat orange sweet potatoes? Iron and zinc don't change the color or taste of foods, but foods that produce vitamin A are often an unearthly orange.
Natural breeding is an accepted practice and if the food production has been able to keep pace with the population growth, it is largely due to hybridization technology of marrying high yielding varieties with traditional ones, though the process takes years to fructify. The green revolution in India has been achieved through this route. The process can be expedited through genetic engineering also which takes much less time but there are safety issues that come in the way of universal acceptance of GM foods. Indisputably the new emerging technologies like genetic engineering hold promise for future in many areas of food production but there has to be a consensus regarding their safety credentials which can be achieved through global cooperation at governmental level in stead of through profit driven private interests.
Can a meat not derived from life size animals be called a vegetarian? There are plant-derived meat substitutes made by texturizing the proteins to give a product with almost same textural characteristics as meat but this type of products are not generally targeted at vegetarian population, their clientele being low income non-vegetarian consumers, not able to buy the real meat. Most of the time they end up as meat extenders, enabling the consumers to get a higher mileage for the meat they can buy. Probably in highly spiced food preparations as in India, the extent of substitutes used may not make much of a difference in the ultimate eating quality. The reported success of Bio-technologists in developing rudimentary meat muscle tissues through stem cell proliferation technique may open up new avenues to make meat-like products for use at least in products based on ground meat.
"Dr. Jim Musick, Vitro's CEO, said, "We are pleased to be involved with this ground breaking opportunity to extend stem cell technology to development of alternative food sources. Cellular immortality as reflected in continual stem cell proliferation (self-renewal) has potential to provide limitless cells that when differentiated to muscle, for example, become the primary ingredient of meat. This reflects the basis of alternative food derived from stem cells that is now being developed. We intend to use our expertise in stem cell media development and commercial manufacture to provide appropriate media formulations to support this nascent technology. Our VITROGROW(TM) Brand of stem cell media has been demonstrated to result in superior performance to competing products in the growth of human adult stem cells and is now utilized in high performance, bio-luminescent test kits (Lumenesc-Hu(TM) and LumiSTEM(TM)) for measuring the quality and potency of mesenchymal and induced-pluripotent stem cells. We anticipate contributing to this exciting new field and plan to further develop cellular immortalization procedures that may be crucial to economic production of stem cell-derived meat." Kedar Challakere, MD, of Mokshagundam Biotechnologies stated, "The in vitro meat products developed thus far have used fetal bovine serum with which to grow their stem cells. The product currently being developed through our contract with Vitro is a synthetic, animal free medium which is anticipated to replace a living organism, the brine shrimp, from the food chain of aquatic creatures."
Probably vegetarians may find it difficult to accept the product as not derived from animals as the researchers used Fetal Bovine Serum for proliferation of the stem cells. Even if animal-free medium is used for proliferation eventually, the starting material, the stem cells still have to come from animal sources. Of course if the technology reaches the stage of commercial exploitation, the meat industry will never be the same as it is to day. The two major criticisms the meat industry is facing to day are massive generation of environment polluting CO2 by the live stock industry and less than 15% conversion of feed grains into meat by the animals, considered a wasteful practice.
Frenetic pace at which energy scientists are pursuing alternate sources of energy, to meet the the contingency arising out of the eventual drying of fossil fuel wells in not distant a future, seems to have taken them to areas not chartered hitherto. It is likely that modern biotechnological tools may yet convert the unheralded single cell organism Algae into a real hero in the coming years. Algae belonging to different varieties are known to be excellent converters of solar energy into different biological constituents such as proteins, colorants, fat, micro nutrients etc and to day it is better known as a health supplement, attributing to it many virtues including longevity. The latest romance with Algae by the fuel scientists is opening up new opportunities as a fuel source capable of replacing fossil fuels that can be used for meeting the modern transportation needs.
"Foreign genes are being spliced into algae and native genes are being tweaked. Different strains of algae are pitted against one another in survival-of-the-fittest contests in an effort to accelerate the evolution of fast-growing, hardy strains. The goal is nothing less than to create superalgae, highly efficient at converting sunlight and carbon dioxide into lipids and oils that can be sent to a refinery and made into diesel or jet fuel. "We've probably engineered over 4,000 strains," said Mike Mendez, a co-founder and vice president for technology at Sapphire Energy, the owner of the laboratory. "My whole goal here at Sapphire is to domesticate algae, to make it a crop." Dozens of companies, as well as many academic laboratories, are pursuing the same goal — to produce algae as a source of, literally, green energy. And many of them are using genetic engineering or other biological techniques, like chemically induced mutations, to improve how algae functions."
It has been known for some time that Algal cells can be manipulated at the gene level to yield hydrocarbons just like the petroleum hydrocarbons but the viability of the bio-conversion route was not established because of low yields. The above studies have been able to show the potential of some Algal variants to be a significant source of hydrocarbons and the findings, though at a laboratory level, are pregnant with far reaching significance to the energy starved humanity. Of course there are many hurdles in realizing the potential and in stead of working in isolation research organizations must pool their resources and experience for evolving a universally acceptable alternate source to fossil fuels and such an achievement will spare precious food resources like grains, sugar beets and sugarcane for meeting the food needs of human beings.